Join us for a live webinar, or attend an in-person event near you.

Want to learn about navigating life with MASH and starting Rezdiffra? Attend our events to hear from Rezdiffra Real Voices™ Patient Ambassadors, get tips from Nurse Educators, and ask questions in a supportive space.

MASH was formerly called NASH (nonalcoholic steatohepatitis).

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Virtual
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Shared Decision-Making

October 30, 6:30 PM ET

In-person
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The Role of Liver Testing

November 1, 10 AM ET
Cincinnati Marriott Northeast
9664 South Mason Montgomery Road, Mason, OH 45040

In-person
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The Role of Liver Testing

November 15, 10 AM CT
The Westin Chicago Northwest
400 Park Boulevard, Itasca, IL 60143

Virtual
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The Role of Liver Testing

November 20, 2 PM ET

In the meantime, review the links below for additional information

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Do you have questions about MASH?

Learn more about fatty liver disease and MASH, how it progresses, and the importance of testing for liver scarring.

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Know the risks

Liver scarring often has no symptoms. If it goes undetected and unmanaged for too long, it can lead to serious health issues.

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Managing your MASH

Learn more about taking Rezdiffra and hear from real patients about their experiences.

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Want to share your story?

If Rezdiffra has made a difference for you, consider becoming an Ambassador.

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Manage your MASH

Learn more about Rezdiffra, a prescription pill taken once per day for adults with MASH with moderate to advanced liver scarring without cirrhosis, along with diet and exercise.

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Check out patient stories

Learn more about taking Rezdiffra and hear from real patients about their experiences.

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Do you know if you have scarring?

Liver scarring often has no symptoms. Ask your liver specialist about testing for MASH with liver scarring today.

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Manage your MASH

Learn more about Rezdiffra, a prescription pill taken once per day for adults with MASH with moderate to advanced liver scarring without cirrhosis, along with diet and exercise.

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Learn more about MASH

Your fatty liver disease may already be MASH with liver scarring. Want to know how you can find out?

Liver with MASH and playback button icon

Show up for your liver

If your fatty liver disease is actually MASH with liver scarring,* there's a treatment option that may be right for you.

With moderate to advanced liver scarring without cirrhosis, along with diet and exercise.

Scarred liver with question mark icon

Do you know if you have scarring?

Liver scarring often has no symptoms. Ask your liver specialist about testing for MASH with living scarring today.

Liver with MASH and playback button icon

Show up for your liver

If your fatty liver disease is actually MASH with liver scarring,* there's a treatment option that may be right for you.

With moderate to advanced liver scarring without cirrhosis, along with diet and exercise.

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Find a specialist who can help

Taking the first step is always hard—but connecting with a specialist who can arrange testing for liver scarring can help make it a lot easier.

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Learn more about MASH and fatty liver disease

Knowledge can be powerful. That’s why knowing which options are available for MASH with moderate to advanced liver scarring without cirrhosis, can help you get a handle on the health of your liver.

Important Safety Information and Indication

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Before you take Rezdiffra, tell your healthcare provider about all of your medical conditions, including if you:

  • have any liver problems other than MASH.
  • have gallbladder problems or have been told you have gallbladder problems, including gallstones.
  • are pregnant or plan to become pregnant. It is not known if Rezdiffra will harm your unborn baby.
  • are breastfeeding or plan to breastfeed. It is not known if Rezdiffra passes into your breast milk. Talk to your healthcare provider about the best way to feed your baby if you take Rezdiffra.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

  • Rezdiffra and other medicines may affect each other, causing side effects. Rezdiffra may affect the way other medicines work, and other medicines may affect how Rezdiffra works.
  • Especially tell your healthcare provider if you take medicines that contain gemfibrozil to help lower your triglycerides, or cyclosporine to suppress your immune system, because Rezdiffra is not recommended in patients taking these medicines.
  • Tell your healthcare provider if you are taking medicines such as clopidogrel to thin your blood or statin medicines to help lower your cholesterol.
  • Know the medicines you take. Keep a list of them to show your healthcare provider and pharmacist when you get a new medicine.

What are the possible side effects of Rezdiffra?

Rezdiffra may cause serious side effects, including:

  • liver injury (hepatotoxicity). Stop taking Rezdiffra and call your healthcare provider right away if you develop the following signs or symptoms of hepatotoxicity: tiredness, nausea, vomiting, fever, rash, your skin or the white part of your eyes turns yellow (jaundice), or stomach pain/tenderness.
  • gallbladder problems. Gallbladder problems such as gallstones, or inflammation of the gallbladder, or inflammation of the pancreas from gallstones can occur with MASH and may occur if you take Rezdiffra. Call your healthcare provider right away if you develop any signs or symptoms of these conditions, including nausea, vomiting, fever, or pain in your stomach area (abdomen) that is severe and will not go away. The pain may be felt going from your abdomen to your back and the pain may happen with or without vomiting.

The most common side effects of Rezdiffra include diarrhea, nausea, itching, stomach pain, vomiting, dizziness, and constipation.

These are not all the possible side effects of Rezdiffra. For more information, ask your healthcare provider or pharmacist.

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1‑800‑FDA‑1088 or www.fda.gov/medwatch. You may also report side effects to Madrigal Pharmaceuticals, Inc. at 1‑800‑905‑0324.

What is Rezdiffra?

Rezdiffra is a prescribed medicine used along with diet and exercise to treat adults with metabolic dysfunction–associated steatohepatitis (MASH) with moderate to advanced liver scarring (fibrosis), but not with cirrhosis of the liver.

This indication is approved based on improvement of MASH and liver scarring (fibrosis). There are ongoing studies to confirm the clinical benefit of Rezdiffra.

Please see the full Prescribing Information, including Patient Information, for Rezdiffra.

Important Safety Information and Indication

Before you take Rezdiffra, tell your healthcare provider about all of your medical conditions, including if you:

  • have any liver problems other than MASH.
  • have gallbladder problems or have been told you have gallbladder problems, including gallstones.
  • are pregnant or plan to become pregnant. It is not known if Rezdiffra will harm your unborn baby.
  • are breastfeeding or plan to breastfeed. It is not known if Rezdiffra passes into your breast milk. Talk to your healthcare provider about the best way to feed your baby if you take Rezdiffra.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

  • Rezdiffra and other medicines may affect each other, causing side effects. Rezdiffra may affect the way other medicines work, and other medicines may affect how Rezdiffra works.
  • Especially tell your healthcare provider if you take medicines that contain gemfibrozil to help lower your triglycerides, or cyclosporine to suppress your immune system, because Rezdiffra is not recommended in patients taking these medicines.
  • Tell your healthcare provider if you are taking medicines such as clopidogrel to thin your blood or statin medicines to help lower your cholesterol.
  • Know the medicines you take. Keep a list of them to show your healthcare provider and pharmacist when you get a new medicine.

What are the possible side effects of Rezdiffra?

Rezdiffra may cause serious side effects, including:

  • liver injury (hepatotoxicity). Stop taking Rezdiffra and call your healthcare provider right away if you develop the following signs or symptoms of hepatotoxicity: tiredness, nausea, vomiting, fever, rash, your skin or the white part of your eyes turns yellow (jaundice), or stomach pain/tenderness.
  • gallbladder problems. Gallbladder problems such as gallstones, or inflammation of the gallbladder, or inflammation of the pancreas from gallstones can occur with MASH and may occur if you take Rezdiffra. Call your healthcare provider right away if you develop any signs or symptoms of these conditions, including nausea, vomiting, fever, or pain in your stomach area (abdomen) that is severe and will not go away. The pain may be felt going from your abdomen to your back and the pain may happen with or without vomiting.

The most common side effects of Rezdiffra include diarrhea, nausea, itching, stomach pain, vomiting, dizziness, and constipation.

These are not all the possible side effects of Rezdiffra. For more information, ask your healthcare provider or pharmacist.

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1‑800‑FDA‑1088 or www.fda.gov/medwatch. You may also report side effects to Madrigal Pharmaceuticals, Inc. at 1‑800‑905‑0324.

What is Rezdiffra?

Rezdiffra is a prescribed medicine used along with diet and exercise to treat adults with metabolic dysfunction–associated steatohepatitis (MASH) with moderate to advanced liver scarring (fibrosis), but not with cirrhosis of the liver.

This indication is approved based on improvement of MASH and liver scarring (fibrosis). There are ongoing studies to confirm the clinical benefit of Rezdiffra.

Please see the full Prescribing Information, including Patient Information, for Rezdiffra.