Tools & Support Support starts here

Tools & Support Support starts here
Support

Madrigal support options

Not an actual card.

Eligible, commercially insured patients may pay as little as $10 with the Rezdiffra Copay Savings Card

Save on Rezdiffra

Eligible, commercially insured patients may pay as little as $10 a month for Rezdiffra with the Copay Savings Card.*

Get the Copay Savings Card

*Eligibility rules apply. Offer not valid for patients enrolled in Medicare, Medicaid, or other federal or state healthcare programs. For program terms, conditions, and eligibility criteria, visit copay.rezdiffra.com.

Working with Madrigal Patient Support

The Madrigal Patient Support program is designed to help you navigate your Rezdiffra treatment journey with confidence. Madrigal Patient Support can help you and your healthcare provider:

  • Understand your insurance coverage and benefits for your treatment
  • Identify any possible financial assistance options
  • Get comprehensive support to guide you through your treatment
Madrigal Patient Support Program

Need help or have questions? Call us at 1-877-219-7770,
Monday-Friday, 8 AM-8 PM ET, or visit

MadrigalPatientSupport.com

Support for those on Medicare Part D

Starting in 2025, the Inflation Reduction Act (IRA) brings new affordability options to Medicare Part D that may help with your prescription drug costs. 

Learn more
Getting Rezdiffra

Rezdiffra, delivered right to you

Once you’re prescribed Rezdiffra, you’ll receive your prescription either through a Specialty Pharmacy in Madrigal’s network or through the Madrigal Patient Support program.

Working with a Specialty Pharmacy

A Specialty Pharmacy stocks medications and treatments that are not typically found at your local retail pharmacy. Specialty Pharmacies are intended to be easy and convenient to work with and will ship your medication directly to you. Here’s how it works:

Your liver specialist or your Madrigal Patient Support Case Manager will send your prescription to a Specialty Pharmacy.

Madrigal Patient Support or the Specialty Pharmacy will confirm and explain medicine costs, coverage, and financial assistance options.

Madrigal Patient Support or the Specialty Pharmacy will call you to schedule the delivery of your medicine.

When it’s time for a refill, Madrigal Patient Support or the Specialty Pharmacy will give you a call.

If you have any questions about your Rezdiffra prescription, your liver specialist or someone on their staff can help you.

Be sure to check your phone

It’s important to answer or return any missed calls from Madrigal Patient Support and your Specialty Pharmacy to keep on track with your medicine. Keep in mind you may not recognize the number.

Resources

Resources and support to help along the way

Get the most out of your next appointment with the help of a Doctor Discussion Guide

Undiagnosed Doctor Discussion Guide
English Español

Wondering if you have NASH with liver scarring?*

Download this Doctor Discussion Guide for help asking your liver specialist about testing for NASH with liver scarring.

Diagnosed Doctor Discussion Guide
English Español

Currently have a NASH with liver scarring* diagnosis?

Download this Doctor Discussion Guide to help you ask your liver specialist if it’s time for Rezdiffra.

Get key information about Rezdiffra in one convenient brochure

View the patient brochure to learn more about NASH with liver scarring, how to manage it, and how Rezdiffra can help.
English Español

Rezdiffra Brochure

Download to learn more about NASH with liver scarring,* how to help manage it, and how Rezdiffra may help.

Moderate to advanced liver scarring (fibrosis) without cirrhosis.

Don’t go it alone—find support for your journey

If you feel like NASH is overwhelming, ask your liver specialist to recommend a local support group. You can also connect with an advocacy group dedicated to helping people with liver diseases, including NASH, such as the ones below.†

Global Liver Institute

The Global Liver Institute is committed to solving problems that matter to people living with liver disease and equipping advocates to improve the lives of all those affected.

Visit the Global Liver Institute
Liver Education Advocates

Liver Education Advocates seeks to raise public awareness of fatty liver disease and MASH, providing support, education, and resources for people with liver disease and their families.

Visit Liver Education Advocates
Fatty liver foundation

The Fatty Liver Foundation helps improve the lives affected by fatty liver disease through awareness, screening, education, and outreach. Get news, information, and support through their LiverSaver Facebook group.

Visit the Fatty Liver Foundation

†The above resources are not controlled, owned, or endorsed by Madrigal, and Madrigal is not responsible for their content.

Become an Ambassador

Already taking Rezdiffra? Your story could inspire others.

Share your Rezdiffra story
Download the Doctor Discussion Guide

Important Safety Information and Indication

Before you take Rezdiffra, tell your healthcare provider about all of your medical conditions, including if you:

  • have any liver problems other than MASH.
  • have gallbladder problems or have been told you have gallbladder problems, including gallstones.
  • are pregnant or plan to become pregnant. It is not known if Rezdiffra will harm your unborn baby.
  • are breastfeeding or plan to breastfeed. It is not known if Rezdiffra passes into your breast milk. Talk to your healthcare provider about the best way to feed your baby if you take Rezdiffra.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

  • Rezdiffra and other medicines may affect each other, causing side effects. Rezdiffra may affect the way other medicines work, and other medicines may affect how Rezdiffra works.
  • Especially tell your healthcare provider if you take medicines that contain gemfibrozil to help lower your triglycerides, or cyclosporine to suppress your immune system, because Rezdiffra is not recommended in patients taking these medicines.
  • Tell your healthcare provider if you are taking medicines such as clopidogrel to thin your blood or statin medicines to help lower your cholesterol.
  • Know the medicines you take. Keep a list of them to show your healthcare provider and pharmacist when you get a new medicine.

What are the possible side effects of Rezdiffra?

Rezdiffra may cause serious side effects, including:

  • liver injury (hepatotoxicity). Stop taking Rezdiffra and call your healthcare provider right away if you develop the following signs or symptoms of hepatotoxicity: tiredness, nausea, vomiting, fever, rash, your skin or the white part of your eyes turns yellow (jaundice), or stomach pain/tenderness.
  • gallbladder problems. Gallbladder problems such as gallstones, or inflammation of the gallbladder, or inflammation of the pancreas from gallstones can occur with MASH and may occur if you take Rezdiffra. Call your healthcare provider right away if you develop any signs or symptoms of these conditions, including nausea, vomiting, fever, or pain in your stomach area (abdomen) that is severe and will not go away. The pain may be felt going from your abdomen to your back and the pain may happen with or without vomiting.

The most common side effects of Rezdiffra include diarrhea, nausea, itching, stomach pain, vomiting, dizziness, and constipation.

These are not all the possible side effects of Rezdiffra. For more information, ask your healthcare provider or pharmacist.

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or www.fda.gov/medwatch. You may also report side effects to Madrigal Pharmaceuticals, Inc. at 1-800-905-0324.

What is Rezdiffra?

Rezdiffra is a prescribed medicine used along with diet and exercise to treat adults with metabolic dysfunction–associated steatohepatitis (MASH) with moderate to advanced liver scarring (fibrosis), but not with cirrhosis of the liver.

This indication is approved based on improvement of MASH and liver scarring (fibrosis). There are ongoing studies to confirm the clinical benefit of Rezdiffra.

Please see the accompanying full Prescribing Information, including Patient Information, for Rezdiffra.